4-morpholinecarboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester
N-BOC-3-hydroxymethylmorpholine
CAS: 473923-56-7
Molecular Formula: C10H19NO4
4-morpholinecarboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester - Names and Identifiers
4-morpholinecarboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C10H19NO4 |
| Molar Mass | 217.26 |
| Density | 1.118±0.06 g/cm3(Predicted) |
| Boling Point | 320.7±27.0 °C(Predicted) |
| Flash Point | 147.8°C |
| Vapor Presure | 2.53E-05mmHg at 25°C |
| pKa | 14.85±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.474 |
4-morpholinecarboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester - Introduction
N-BOC-3-hydroxymethylmorpholine(N-BOC-3-hydroxymethylmorpholine) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White solid
-Molecular formula: C12H21NO4
-Molecular weight: 247.3g/mol
-Melting point: 70-72 degrees Celsius
-Boiling point: 338.5 degrees Celsius (expected)
-Solubility: Soluble in some organic solvents such as dichloromethane and ethanol
Use:
- N-BOC-3-hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester is a compound with functional groups, commonly used in organic synthesis as a temporary protective agent for protecting groups (protecting hydroxyl or amine groups).
-It is often used in the synthesis of some biologically active compounds in drug synthesis.
Preparation Method:
N-BOC-3-hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester can be prepared by the following steps:
-Step 1: N-BOC morpholine and formaldehyde are reacted to generate 3-hydroxymethylmorpholine.
-Step 2: The product obtained in step 1 is reacted with tert-butanol and dimethyl sulfoxide, and an excess of triformamidine is added at low temperature to obtain tert-butyl N-BOC-3-hydroxymethylmorpholine-4-carboxylate.
Safety Information:
- N-BOC-3-Hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester should be stored in a dry, cool place.
-During operation, care should be taken to avoid inhaling the dust, vapor or smoke of the compound.
-Wear suitable personal protective equipment such as chemical protective gloves, eye protection and chemical protective face mask when using.
-Follow all relevant safety procedures during storage and handling.
Nature:
-Appearance: White solid
-Molecular formula: C12H21NO4
-Molecular weight: 247.3g/mol
-Melting point: 70-72 degrees Celsius
-Boiling point: 338.5 degrees Celsius (expected)
-Solubility: Soluble in some organic solvents such as dichloromethane and ethanol
Use:
- N-BOC-3-hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester is a compound with functional groups, commonly used in organic synthesis as a temporary protective agent for protecting groups (protecting hydroxyl or amine groups).
-It is often used in the synthesis of some biologically active compounds in drug synthesis.
Preparation Method:
N-BOC-3-hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester can be prepared by the following steps:
-Step 1: N-BOC morpholine and formaldehyde are reacted to generate 3-hydroxymethylmorpholine.
-Step 2: The product obtained in step 1 is reacted with tert-butanol and dimethyl sulfoxide, and an excess of triformamidine is added at low temperature to obtain tert-butyl N-BOC-3-hydroxymethylmorpholine-4-carboxylate.
Safety Information:
- N-BOC-3-Hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester should be stored in a dry, cool place.
-During operation, care should be taken to avoid inhaling the dust, vapor or smoke of the compound.
-Wear suitable personal protective equipment such as chemical protective gloves, eye protection and chemical protective face mask when using.
-Follow all relevant safety procedures during storage and handling.
Last Update：2024-04-09 19:05:49
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Product Name: 3-HYDROXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER Visit Supplier Webpage Request for quotation
CAS: 473923-56-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 473923-56-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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